Cell competition drives bronchiolization and pulmonary fibrosis

Abstract Idiopathic pulmonary fibrosis (IPF) is a progressive respiratory scarring disease arising from the maladaptive differentiation of lung stem cells into bronchial epithelial cells rather than into alveolar type 1 (AT1) cells, which are responsible for gas exchange. Here, we report that health...

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Bibliographic Details
Main Authors: Rachel Warren, Kylie Klinkhammer, Handeng Lyu, Joseph Knopp, Tingting Yuan, Changfu Yao, Barry Stripp, Stijn P. De Langhe
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54997-2
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