β-adrenergic receptor inhibits heart regeneration by downregulating Yap m6A modification

Abstract Newborn mammals transiently maintain the heart regenerative capacity. β-adrenergic receptor (β-AR) is the most critical receptor in regulating cardiomyocyte behavior. However, the role and mechanism of β-AR, especially the subtypes of β-AR, in heart regeneration remain unclear. Here, we rev...

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Bibliographic Details
Main Authors: Kaihang Guan, Zijian Li
Format: Article
Language:English
Published: Nature Publishing Group 2025-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07642-9
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