Interfacial Engineering-Free Microfluidics: Toward a Mild and Cost-Effective Strategy for Surfactant- and Demulsifier-Free Hydrogel Microsphere Fabrication

Interfacial Engineering-Free Microfluidics: Toward a Mild and Cost-Effective Strategy for Surfactant- and Demulsifier-Free Hydrogel Microsphere Fabrication

This study proposes a simple yet versatile microfluidic strategy for fabricating monodisperse alginate hydrogel microspheres using a symmetric flow-focusing device. The system integrates three key innovations: (1) Cost-effective mold fabrication: A paper-based positive master replaces conventional S...

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Bibliographic Details
Main Authors: Qing Qin, Yu Zhang, Yubei Wei, Jinnuo Lv, Meiling Tian, Yuanyuan Sun, Wei Fang, Xingjian Huang, Jianglin Li, Yifeng Su, Xiaoliang Xiang, Xing Hu, Zhizhi Zhou
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Micromachines
Subjects:
hydrogel microsphere
microfluidics
demulsifier-free
surfactant-free
droplet formation
non-lithography
Online Access:https://www.mdpi.com/2072-666X/16/7/733
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