Design, synthesis, anticancer properties, and molecular docking of imidazolone derivatives with lipophilic moiety

Abstract As part of an ongoing investigation into imidazolone derivatives with anticancer activities, herein we present the synthesis of a new series of imidazolones with various substituents, including lipophilic and hydrophilic. All synthesized imidazolones (3a–3g and 5a–5g) were characterized by...

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Bibliographic Details
Main Authors: Oswa Fares, Othman Hamed, Mohyeddin Assali, Avni Berisha, Haythem Saadeh, Bahia Abu Lail, Omar Dagdag, Abdullah Samaro, Waseem Mansour, Nidal Jaradat, Saber Abu-Jabal
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-97478-2
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