Lactoferrin exhibits PEDV antiviral activity by interfering with spike-heparan sulfate proteoglycans binding and activating mucosal immune response

Lactoferrin exhibits PEDV antiviral activity by interfering with spike-heparan sulfate proteoglycans binding and activating mucosal immune response

Abstract Neonatal piglets infected with Porcine Epidemic Diarrhea Virus (PEDV) experience a mortality rate of up to 90%, resulting in significant economic losses to the swine industry in China. Current strategies using specific antibodies in sow milk to prevent Porcine Epidemic Diarrhea (PED) in the...

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Bibliographic Details
Main Authors: Peng Liu, Jinjiao Zuo, Hui Lu, Bin Zhang, Caihong Wu
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Veterinary Research
Subjects:
Lactoferrin
PEDV
heparan sulfate proteoglycans
mucosal immunity
neonatal piglets
Online Access:https://doi.org/10.1186/s13567-025-01456-5
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