Improved prediction of MAPKi response duration in melanoma patients using genomic data and machine learning

Abstract Baseline genomic data have not demonstrated significant value for predicting the response duration to MAPK inhibitors (MAPKi) in patients with advanced BRAFV600-mutated melanoma. We used machine learning algorithms and pre-processed genomic data to test whether they could contain useful inf...

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Bibliographic Details
Main Authors: Sarah Dandou, Kriti Amin, Véronique D’Hondt, Jérôme Solassol, Olivier Dereure, Peter J. Coopman, Ovidiu Radulescu, Holger Fröhlich, Romain M. Larive
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-025-00814-y
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