Multimodal tumor microenvironment signature of colorectal cancer for prediction prognosis and chemotherapy benefit

Multimodal tumor microenvironment signature of colorectal cancer for prediction prognosis and chemotherapy benefit

Abstract The current tumor‒node‒metastasis (TNM) staging system cannot provide sufficient information for prognosis and chemotherapy benefits in patients with colorectal cancer (CRC). The tumor microenvironment plays a critical role in disease progression and therapeutic response. Here, we developed...

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Main Authors: Wei Jiang, Kun Yang, Chanchan Xiao, Hongli Ji, Botao Yan, Shuhan Zhao, Biao Zhang, Jiaxin Cheng, Shuoyu Xu, Guangxing Wang, Zexi Lin, Jianping Lu, Gang Chen, Shuangmu Zhuo, Jun Yan
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-025-01069-3
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https://doi.org/10.1038/s41698-025-01069-3

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