The effect of NF-kB and MAPK mediated Proinflammatory microenvironment on renal aging and amyloid deposition in elder rats

The effect of NF-kB and MAPK mediated Proinflammatory microenvironment on renal aging and amyloid deposition in elder rats

Abstract Low-grade inflammation associated with the aging process exerts functional and morphological effects on multiple organs. The kidney is an organ that is severely affected by the aging process. Our study aimed to determine the relationship between histopathological and immunohistochemical cha...

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Bibliographic Details
Main Authors: Mete Keçeci, Cenk Murat Özer, Esra Babaoğlu, Furkan Bodur, Ali Can Önal, Ayşe Zeynep Yılmazer Kayatekin, Osman Cengil, Ali Serdar Karataş
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Aging
Inflammation
NF-κB
MAPK
TNF-α
IL-6
Online Access:https://doi.org/10.1038/s41598-025-14559-y
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https://doi.org/10.1038/s41598-025-14559-y

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