Karyotype evolution in response to chemoradiotherapy and upon recurrence of esophageal adenocarcinomas

Karyotype evolution in response to chemoradiotherapy and upon recurrence of esophageal adenocarcinomas

Summary: The genome of esophageal adenocarcinoma (EAC) is highly unstable and might evolve over time. Here, we track karyotype evolution in EACs in response to treatment and upon recurrence through multi-region and longitudinal analysis. To this end, we introduce L-PAC (low-purity inference of absol...

Full description

Saved in:
Bibliographic Details
Main Authors: Karen van der Sluis, Johanna W. van Sandick, Willem J. Koemans, Tom van den Bosch, Annegien Broeks, Dennis Peters, Iris M. Seignette, Christian R. Rausch, Erik van Dijk, Petur Snaebjornsson, José G. van den Berg, Nicole C.T. van Grieken, Bauke Ylstra, Beatriz Carvalho, Daniël M. Miedema, Liudmila L. Kodach
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Cell Reports
Subjects:
CP: Cancer
CP: Genomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724013329
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S2211124724013329

Similar Items