Incorporation of graphene oxide into collagenous biomaterials attenuates scar-forming phenotype transition of reactive astrocytes in vitro

The integrin-mediated interaction between collagen type I and reactive astrocytes was recently shown to induce a detrimental, scar-forming phenotype transformation following spinal cord injury (SCI), which severely limits the therapeutic potential of commonly used collagen-based biomaterials. Graphe...

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Bibliographic Details
Main Authors: Kest Verstappen, Alexey Klymov, Paula A.A.P. Marques, Sander C.G. Leeuwenburgh, X. Frank Walboomers
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Brain Research Bulletin
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Online Access:http://www.sciencedirect.com/science/article/pii/S0361923025001923
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