MDM1 overexpression promotes p53 expression and cell apoptosis to enhance therapeutic sensitivity to chemoradiotherapy in patients with colorectal cancer

Objective: Identifying biomarkers that predict the efficacy and prognosis of chemoradiotherapy is important for individualized clinical treatment. We previously reported that high murine double minute 1 (MDM1) expression in patients with rectal cancer is linked to a favorable chemoradiation response...

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Main Authors: Ningxin Ren, Hongxia Chen, Ying Huang, Jing Jin, Shaosen Zhang, Ruoqing Yan, Mengjie Li, Linlin Zheng, Shuangmei Zou, Yexiong Li, Wen Tan, Dongxin Lin
Format: Article
Language:English
Published: China Anti-Cancer Association 2025-03-01
Series:Cancer Biology & Medicine
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Online Access:https://www.cancerbiomed.org/content/22/3/266
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