Abnormal Cellular Populations Shape Thymic Epithelial Tumor Heterogeneity and Anti‐Tumor by Blocking Metabolic Interactions in Organoids

Abnormal Cellular Populations Shape Thymic Epithelial Tumor Heterogeneity and Anti‐Tumor by Blocking Metabolic Interactions in Organoids

Abstract A variety of abnormal epithelial cells and immature and mature immune cells in thymic epithelial tumors (TETs) affect histopathological features, the degree of malignancy, and the response to treatment. Here, gene expression, trajectory inference, and T cell antigen receptor (TCR)‐based lin...

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Main Authors: Xuefei Liu, Changchun Wang, Yueyu Huang, Qiaoli Lv, Chang Yu, Jianghua Ying, Lianhui Duan, Yangzhong Guo, Guanyin Huang, Wenhui Shen, Ming Jiang, Weimin Mao, Zhixiang Zuo, An Zhao
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Advanced Science
Subjects:
histopathology
ionocyte
KRT14+ progenitor cells
metabolic interaction
thymic epithelial tumors
Online Access:https://doi.org/10.1002/advs.202406653
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https://doi.org/10.1002/advs.202406653

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