The antioxidant property of CAPE depends on TRPV1 channel activation in microvascular endothelial cells

The antioxidant property of CAPE depends on TRPV1 channel activation in microvascular endothelial cells

Caffeic acid phenethyl ester (CAPE) is a hydrophobic phytochemical typically found in propolis that acts as an antioxidant, anti-inflammatory and cardiovascular protector, among several other properties. However, the molecular entity responsible for recognising CAPE is unknown, and whether that mole...

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Main Authors: Miltha Hidalgo, Bárbara Railef, Vania Rodríguez, Carolina Navarro, Vanessa Rubio, Jorge Meneses-Pacheco, Sandra Soto-Alarcón, Christine Kreindl, Carolina Añazco, Leandro Zuñiga, Omar Porras
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Redox Biology
Subjects:
CAPE
Caffeic acid
TRPV1
Endothelial cells
HyPer
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231725000205
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