Study on the mechanism of action of berberine combined with Jianpi Yishen Huazhuo formulation in treating obese polycystic ovary syndrome by activating PI3K/AKT signaling pathway

Objectives This study aims to investigate the effects and potential mechanisms of berberine in conjunction with Jianpi Yishen Huazhuo formulation (JPYSHZF) on obese rats that serve as a model for polycystic ovary syndrome (PCOS).Methods Letrozole combined with high-fat diet (HFD) was used to establi...

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Bibliographic Details
Main Authors: Xiaojing Zhang, Dejiang Ji, Yan Zhang, Cuizhong Du, Lijun Liang, Aqsa Ahmad, Yahong Feng, Gaxi Ye
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Gynecological Endocrinology
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Online Access:https://www.tandfonline.com/doi/10.1080/09513590.2025.2462068
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