ALDH18A1 has carcinogenic functions and regulates alternative splicing events of DNA repair-related genes in esophageal carcinoma cells

ALDH18A1 has carcinogenic functions and regulates alternative splicing events of DNA repair-related genes in esophageal carcinoma cells

Abstract Esophageal carcinoma (ESCA) is a common tumor in the digestive system, resulting in approximately 300,000 death worldwide every year. ALDH18A1, a potential RNA binding protein (RBP), is significantly overexpressed as in ESCA, while its functions and mechanism is unclear. In this study, we s...

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Bibliographic Details
Main Authors: Wang Yongkang, Maimaiti Yisireyili, Kelimu Abudureyimu, Atsushi Enomoto
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Esophageal carcinoma
ALDH18A1
RNA-binding protein
Alternative splicing
Gene expression
Online Access:https://doi.org/10.1038/s41598-025-08006-1
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https://doi.org/10.1038/s41598-025-08006-1

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