Screening and prevention of gynecologic malignancies in patients with lynch syndrome: following the guidelines

Lynch syndrome (LS), a hereditary condition caused by germline mutations in mismatch repair (MMR) genes, significantly elevates the lifetime risk of endometrial cancer (EC) (40–60%) and ovarian cancer (8–10%) in affected women. Despite advances in colorectal cancer screening for LS patients, optimal...

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Bibliographic Details
Main Authors: Chen Ben David, Yoav Siegler, Revital Linder, Amnon Amit, Emad Matanes
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1563022/full
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