Potential confounding mutations in Keio knockout strains: implications for research accuracy

ABSTRACT The Keio library of single-gene knock-out mutants of Escherichia coli is useful for the research community. It has been used to analyze the role of various E. coli genes in alcohol tolerance, multi-drug resistance, and biofilm formation. The current study provides a general overview of pote...

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Bibliographic Details
Main Authors: Oishi Sen, Xianghui Liu, Staffan Kjelleberg, Scott A. Rice, Thomas Seviour
Format: Article
Language:English
Published: American Society for Microbiology 2025-05-01
Series:Microbiology Spectrum
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Online Access:https://journals.asm.org/doi/10.1128/spectrum.02036-24
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