Changes in alpha-fetoprotein across the systemic therapy continuum in advanced hepatocellular carcinoma—a real-world, multicenter study

Changes in alpha-fetoprotein across the systemic therapy continuum in advanced hepatocellular carcinoma—a real-world, multicenter study

Background: Early changes in alpha-fetoprotein (AFP) are a promising surrogate endpoint for systemic treatment outcomes in hepatocellular carcinoma (HCC). Objectives: We sought to investigate the utility of AFP response across first-line sorafenib (1L SOR) and later-line checkpoint inhibitor (CPI) t...

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Main Authors: Michael Li, Lindsay M. Hannan, Lipika Goyal, Andrea G. Bocobo, Anna L. Parks, Kelly Bauer, Islam Baiev, Caroline Dinicola, John D. Gordan, Alan P. Venook, William P. Harris, Paige Bracci, Robin K. Kelley
Format: Article
Language:English
Published: SAGE Publishing 2024-11-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/17588359241297085
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https://doi.org/10.1177/17588359241297085

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