Comprehensive analysis of keloid super-enhancer networks reveals FOXP1-mediated anti-senescence mechanisms in fibrosis

Abstract There is a significant gap in multi-omics studies on keloids, especially concerning the interaction between fibroblasts and super-enhancers (SEs). Identifying novel biomarkers within the epigenetic landscape could greatly improve keloid management. In this study, we investigated gene expres...

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Bibliographic Details
Main Authors: Hao Yang, Dongming Lv, Xiaohui Li, Yongfei Chen, Hailin Xu, Honglin Wu, Zhiyong Wang, Xiaoling Cao, Bing Tang, Wuguo Deng, Jiayuan Zhu, Zhicheng Hu
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Cellular & Molecular Biology Letters
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Online Access:https://doi.org/10.1186/s11658-025-00763-1
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