Preimplantation genetic testing for monogenic disorders to prevent MSH6 germline pathogenic variant related colorectal cancer

Abstract Background Colorectal cancer (CRC) is the third most deadly cancer in the world, accounting for approximately 10% of all cancer diagnoses and cancer-related deaths worldwide each year. In addition to recognized risk factors such as obesity, physical inactivity, and smoking, genetic predispo...

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Bibliographic Details
Main Authors: Wenhua Wang, Zheng Zhou, Xi Cheng, Li Chen, Jun Jing, Chao Chen, Jie Dong, Hui Chen, Jinzhao Ma, Bing Yao
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Cancer
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Online Access:https://doi.org/10.1186/s12885-025-14226-5
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