Human XIST: Origin and Divergence of a <i>cis</i>-Acting Silencing RNA

Dimorphism of sex chromosomes often leads to a need for dosage compensation. In eutherian mammals, XIST, a long non-coding RNA, is expressed from the X chromosome that will be silenced, triggering X-chromosome inactivation (XCI). XIST originated from the ancestral protein-coding <i>Lnx3</i&...

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Bibliographic Details
Main Authors: Maria Jose Navarro-Cobos, Carolyn J. Brown
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Non-Coding RNA
Subjects:
Online Access:https://www.mdpi.com/2311-553X/11/3/35
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