Effect of spironolactone on monocyte subsets in atrial fibrillation: IMPRESS-AF randomised controlled trial

Abstract Background Monocyte subsets differentially influence pathophysiology of heart failure and atrial fibrillation (AF) through inflammation, fibrosis, and angiogenesis. Spironolactone has antifibrotic properties. This study investigated the effect spironolactone on monocyte subsets and monocyte...

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Bibliographic Details
Main Authors: Farhan Shahid, Eduard Shantsila, Alena Shantsila, Gregory Y H Lip
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-024-74592-1
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