Engineered Exosomes Carrying Super-Repressor IκB Reduced Biliary Atresia-Induced Liver Fibrosis in Minipig and Mouse Models

Engineered Exosomes Carrying Super-Repressor IκB Reduced Biliary Atresia-Induced Liver Fibrosis in Minipig and Mouse Models

<b>Background and Aim:</b> Biliary atresia is a rare, progressive disease that affects the bile ducts in newborns. Persistent bile duct obstruction induces various pathological conditions, including jaundice, inflammation, and liver fibrosis; however, the exact pathogenesis of biliary at...

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Bibliographic Details
Main Authors: Jisoo Kang, Cheolhyoung Park, Hanoul Yun, Chulhee Choi, Wonhyo Seo
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Pharmaceutics
Subjects:
biliary atresia
liver fibrosis
engineered exosome
super-repressor IκB
Online Access:https://www.mdpi.com/1999-4923/17/2/264
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