Circulating YKL-40 levels but not CHI3L1 or TRIB1 gene variants predict long-term outcomes in patients with angiographically confirmed multivessel coronary artery disease

Circulating YKL-40 levels but not CHI3L1 or TRIB1 gene variants predict long-term outcomes in patients with angiographically confirmed multivessel coronary artery disease

Abstract YKL-40 is significantly associated with the prevalence and severity of coronary artery disease (CAD). YKL-40 levels are significantly associated with variations in the CHI3L1 and TRIB1 genes. We investigated candidate genes for YKL-40 levels and evaluated the prognostic value of this biomar...

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Bibliographic Details
Main Authors: Hsin-Hua Chou, Ming-Sheng Teng, Jyh-Ming Jimmy Juang, Fu-Tien Chiang, I-Shiang Tzeng, Semon Wu, Yu-Lin Ko
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
YKL-40
CHI3L1
TRIB1
Weighted genetic risk score
Taiwan Biobank
Coronary artery disease
Online Access:https://doi.org/10.1038/s41598-024-81190-8
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https://doi.org/10.1038/s41598-024-81190-8

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