Deep-learning structure elucidation from single-mutant deep mutational scanning

Abstract Deep learning has revolutionized the field of protein structure prediction. AlphaFold2, a deep neural network, vastly outperformed previous algorithms to provide near atomic-level accuracy when predicting protein structures. Despite its success, there still are limitations which prevent acc...

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Bibliographic Details
Main Authors: Zachary C. Drake, Elijah H. Day, Paul D. Toth, Steffen Lindert
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62261-4
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