Type 1 diabetes mellitus (T1DM) does not affect whole blood responses to alginate-based microspheres despite plasma lipid and glucose differences

Type 1 diabetes mellitus (T1DM) does not affect whole blood responses to alginate-based microspheres despite plasma lipid and glucose differences

Encapsulation of insulin-producing cells holds significant therapeutic potential for treating type 1 diabetes (T1DM). The impact of diabetic conditions on host responses is not well understood. This study is the first to compare ex-vivo whole blood responses to alginate microbeads in T1DM subjects v...

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Main Authors: Kalaiyarasi Vasuthas, Sverre Christian Christiansen, Joachim Sebastian Kjesbu, Liv Ryan, Trygve Andreassen, Geir Slupphaug, Berit L. Strand, Jørgen Stenvik, Anne Mari A. Rokstad
Format: Article
Language:English
Published: Elsevier 2025-10-01
Series:Materials Today Bio
Subjects:
Alginate microspheres
Lipoproteins
Sulfated alginate
Immune response
T1DM
Whole blood model
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006425006830
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