IncRNA IPAN antagonizes RIG-I/TRIM25-mediated degradation of influenza A virus PB1 to promote viral replication

IncRNA IPAN antagonizes RIG-I/TRIM25-mediated degradation of influenza A virus PB1 to promote viral replication

The productive infection of influenza A virus (IAV) requires the functional involvement of host long noncoding ribonucleic acids (lncRNAs). Identification of key cellular lncRNAs and elucidation of their molecular mechanisms in IAV replication are expected to expand our understanding of virus-host i...

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Bibliographic Details
Main Authors: Tingting Sun, Shumin Chen, Rui Zhou, Saisai Guo, Yilu Ye, Jingyi Qiu, Xiaoyu Li, Shan Cen, Jing Wang
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Biosafety and Health
Subjects:
Long noncoding ribonucleic acids (lncRNAs)
Influenza A virus (IAV)
Influenza virus PB1-associated long noncoding RNA (IPAN)
Degradation
Retinoic acid-inducible gene I (RIG-I)
Tripartite motif-containing protein 25 (TRIM25)
Online Access:http://www.sciencedirect.com/science/article/pii/S2590053625000710
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