Dual-pathway targeted therapy for Parkinson's disease: Biomimetic nanosomes inhibit ferroptosis and pyroptosis through NLRP3 inflammasome regulation

Dual-pathway targeted therapy for Parkinson's disease: Biomimetic nanosomes inhibit ferroptosis and pyroptosis through NLRP3 inflammasome regulation

Parkinson's disease (PD), a progressive neurodegenerative disorder, is marked by the degeneration of dopaminergic neurons. Emerging evidence highlights the critical involvement of neuronal ferroptosis and microglial pyroptosis in PD pathogenesis. In this study, we first characterized systemic i...

Full description

Saved in:
Bibliographic Details
Main Authors: Yi Wang, Xuemei Liao, Qinglong Guo, Heng Zhang, Lei Ye, Liangchen Yu, Xiaoming Kong, Yicheng Jiang, Peng Zhao, Kaiyong Cai, Hongwei Cheng
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-09-01
Series:Bioactive Materials
Subjects:
Parkinson's disease
BV2 membrane
Selenium
Ferroptosis
Pyroptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X25002701
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S2452199X25002701

Similar Items