Impact of physiological media on acute myeloid leukemia bioenergetics and cell proliferation

Impact of physiological media on acute myeloid leukemia bioenergetics and cell proliferation

Abstract Increasing emphasis has been placed on improving the physiological relevance of cell culture media with formulations such as Human Plasma-Like Medium (HPLM). Given that shifts in mitochondrial metabolism and nutrient use are emerging as anti-cancer targets, the present study sought to inves...

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Main Authors: Brett R. Chrest, McLane M. Montgomery, Raphael T. Aruleba, Polina Krassovskaia, Emely A. Pacheco, James. T. Hagen, Kayla J. Vandiver, Kang Tung, Molly K. Alexander, Nicholas C. Williamson, Joshua G. Taylor, Riley N. Bessetti, Heather A. Belcher, Filip Jevtovic, Zoe S. Terwilliger, Everett C. Minchew, Tonya N. Zeczycki, Linda May, Nicholas T. Broskey, Christopher B. Geyer, Karen Litwa, Espen E. Spangenburg, Johanna L. Hannan, Jessica M. Ellis, Joseph M. McClung, P. Darrell Neufer, Kelsey H. Fisher-Wellman
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Cancer & Metabolism
Online Access:https://doi.org/10.1186/s40170-025-00395-1
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https://doi.org/10.1186/s40170-025-00395-1

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