Multi-cohort analysis identifies a blood-based immune transcriptomic signature for early lung cancer detection

Abstract Early diagnosis of lung cancer is critical for timely intervention and reducing mortality. The immune system and cancer are intricately linked, which provides a unique opportunity to monitor changes in the immune system as a biomarker of cancer development. We collected bulk blood transcrip...

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Bibliographic Details
Main Authors: Hong Zheng, Aditya M. Rao, Ananthakrishnan Ganesan, Hyongsok Tom Soh, Bruce AJ Ponder, Robert C. Rintoul, Purvesh Khatri
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-025-01043-z
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