Wuzang Wenyang Huayu Tang Treatment of vascular dementia by modulation of BCL-2/BAX/Caspase3: An integrated in vitro cellular assay and network pharmacological analysis

Wuzang Wenyang Huayu Tang Treatment of vascular dementia by modulation of BCL-2/BAX/Caspase3: An integrated in vitro cellular assay and network pharmacological analysis

Objective: This project explores Wuzang Wenyang Huayu Tang (WWHT) 's potential mechanisms for treating vascular dementia (VD) based on network pharmacology and experimental validation. Methods: TCMSP was used to screen the active ingredients and targets of WWHT; GeneCards was used to identify V...

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Bibliographic Details
Main Authors: Yu-Cheng Lu, Yu-Fu Zeng, Yan-Chun Li, Chun-Mei Liang, Ying-Ying Cao, Ling Zhang, Meng-Qi Li, Jia-Jia Zhong, Li-Mei Liang
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Pharmacological Research - Modern Chinese Medicine
Subjects:
Vascular dementia
Wuzang Wenyang Huayu Tang
Network pharmacological
Molecular docking
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S266714252500020X
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