REDOX Imbalance and Oxidative Stress in the Intervertebral Disc: The Effect of Mechanical Stress and Cigarette Smoking on ER Stress and Mitochondrial Dysfunction

REDOX Imbalance and Oxidative Stress in the Intervertebral Disc: The Effect of Mechanical Stress and Cigarette Smoking on ER Stress and Mitochondrial Dysfunction

Low back pain is a widespread condition that significantly impacts quality of life, with intervertebral disc degeneration (IDD) being a major contributing factor. However, the underlying mechanisms of IDD remain poorly understood, necessitating further investigation. Environmental risk factors, such...

Full description

Saved in:
Bibliographic Details
Main Authors: Hui Li, Joshua Kelley, Yiqing Ye, Zhi-Wei Ye, Danyelle M. Townsend, Jie Zhang, Yongren Wu
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Cells
Subjects:
low back pain
intervertebral disc degeneration
environmental risk factors
reactive oxygen species
redox imbalance
endoplasmic reticulum stress
Online Access:https://www.mdpi.com/2073-4409/14/8/613
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/2073-4409/14/8/613

Similar Items