Characterizing variability in passive myocardial stiffness in healthy human left ventricles using personalized MRI and finite element modeling

Characterizing variability in passive myocardial stiffness in healthy human left ventricles using personalized MRI and finite element modeling

Abstract Abnormal passive stiffness of the heart muscle (myocardium) is evident in the pathophysiology of several cardiovascular diseases, making it an important indicator of heart health. Recent advancements in cardiac imaging and biophysical modeling now enable more effective evaluation of this bi...

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Bibliographic Details
Main Authors: Fikunwa O. Kolawole, Vicky Y. Wang, Bianca Freytag, Michael Loecher, Tyler E. Cork, Martyn P. Nash, Ellen Kuhl, Daniel B. Ennis
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Cardiac mechanics
In vivo cardiac MRI
Inverse FEM
Passive myocardial stiffness
Online Access:https://doi.org/10.1038/s41598-025-89243-2
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https://doi.org/10.1038/s41598-025-89243-2

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