Development of nucleic acid extraction-free one-step real-time RT-PCR for diagnosis of SARS-CoV-2 infection

Introduction: The aim of this study is to develop a one-step real-time PCR assay for SARS-CoV-2 detection. The study was designed to circumvent the routine RNA isolation step and to optimize a lysis buffer and parameters for direct quantitative PCR. Methodology: A lysis solution was prepared usin...

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Bibliographic Details
Main Authors: Arbind Kumar, Arun Kumar, Yogendra Padwad, Shaifali Sharma, Sanjay Kumar
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2025-06-01
Series:Journal of Infection in Developing Countries
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Online Access:https://www.jidc.org/index.php/journal/article/view/18079
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