Metabolic reprogramming in hepatocellular carcinoma: mechanisms of immune evasion and therapeutic implications

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide, with limited treatment options for advanced stages. Metabolic reprogramming is a hallmark of cancer, enabling tumor cells to adapt to the harsh tumor microenvironment (TME) and evade immune surveillance. This revie...

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Bibliographic Details
Main Authors: Bocheng Gao, Yan Lu, Xingyue Lai, Xi Xu, Shuhua Gou, Zhida Yang, Yanju Gong, Hong Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1592837/full
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