Purinosomes as a therapeutic target in hepatocellular carcinoma: insights and opportunities
Abstract The formation of purinosomes, dynamic complexes involved in de novo purine biosynthesis, has been recognized as a critical process for cell growth. Although their upregulation in cancer cells suggests their potential as a therapeutic target, the specific role of purinosomes in hepatocellula...
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| Main Authors: | Zhen Lin, Jia-Wei Long, Ming-chun Zhao, Pin Guo, Jin Wen, Guang-Liang Chen |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-04-01
|
| Series: | Discover Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s12672-025-02366-w |
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