Identifying cross-tissue molecular targets of lung function by multi-omics integration analysis from DNA methylation and gene expression of diverse human tissues
Abstract Background Previous studies have reported several genetic loci associated with lung function. However, the mediating mechanism between these genetic loci and lung function phenotype is rarely explored. In this research, we used a cross-tissue multi-omics post-GWAS analysis to explain the as...
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| Main Authors: | Shisheng Peng, Jinlong Fang, Weiliang Mo, Guodong Hu, Senquan Wu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-03-01
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| Series: | BMC Genomics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12864-025-11476-2 |
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