ONC201 (Dordaviprone) Induces Integrated Stress Response and Death in Cervical Cancer Cells

Cervical cancer is a leading cause of death in women globally. Systemic chemotherapy offers only limited therapeutic benefit for advanced-stage disease due to toxicity and drug resistance. ONC201 (also known as TIC10 or dordaviprone) is a TRAIL (TNF-Related Apoptosis-Inducing Ligand) and cIpP (casei...

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Bibliographic Details
Main Authors: Sneha O. Pathak, Sonal M. Manohar
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/15/4/463
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