Bat RNA viruses employ viral RHIMs orchestrating species-specific cell death programs linked to Z-RNA sensing and ZBP1-RIPK3 signaling

Bat RNA viruses employ viral RHIMs orchestrating species-specific cell death programs linked to Z-RNA sensing and ZBP1-RIPK3 signaling

Summary: RHIM is a protein motif facilitating the assembly of large signaling complexes triggering regulated cell death. A few DNA viruses employ viral RHIMs mimicking host RHIMs and counteract cell death by interacting with host RHIM-proteins to alleviate antiviral defenses. Whether RNA viruses ope...

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Main Authors: Sanchita Mishra, Disha Jain, Ayushi Amin Dey, Sahana Nagaraja, Mansi Srivastava, Oyahida Khatun, Keerthana Balamurugan, Micky Anand, Avinash Karkada Ashok, Shashank Tripathi, Mahipal Ganji, Sannula Kesavardhana
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:iScience
Subjects:
Molecular biology
Immunology
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224026713
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http://www.sciencedirect.com/science/article/pii/S2589004224026713

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