Structures of complete extracellular assemblies of type I and type II Oncostatin M receptor complexes

Abstract Oncostatin M (OSM) is a unique Interleukin 6 (IL-6) family cytokine that plays pivotal roles in numerous biological events by signaling via two types of receptor complexes. While type I OSM receptor complex is formed by glycoprotein 130 (gp130) heterodimerization with Leukemia Inhibitory Fa...

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Bibliographic Details
Main Authors: Yi Zhou, Panayiotis E. Stevis, Jing Cao, George Ehrlich, Jennifer Jones, Ashique Rafique, Mark W. Sleeman, William C. Olson, Matthew C. Franklin
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54124-1
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