Phage-antibiotic combinations against Klebsiella pneumoniae: impact of methodological approaches on effect evaluation

Phage-antibiotic combinations against Klebsiella pneumoniae: impact of methodological approaches on effect evaluation

BackgroundThe combined use of bacteriophages and antibiotics represents a promising strategy for combating multidrug-resistant bacterial pathogens. However, the lack of uniformity in methods for assessing combination effects and experimental protocols has resulted in inconsistent findings across stu...

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Main Authors: Roman B. Gorodnichev, Anastasiia O. Krivulia, Maria A. Kornienko, Narina K. Abdraimova, Maja V. Malakhova, Marina V. Zaychikova, Dmitry A. Bespiatykh, Valentin A. Manuvera, Egor A. Shitikov
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Microbiology
Subjects:
phage
antibiotic
capsule depolymerase
synergy
antagonism
Klebsiella pneumoniae
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1530819/full
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https://www.frontiersin.org/articles/10.3389/fmicb.2025.1530819/full

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