CPEB4 modulates liver cancer progression by translationally regulating hepcidin expression and sensitivity to ferroptosis

CPEB4 modulates liver cancer progression by translationally regulating hepcidin expression and sensitivity to ferroptosis

Background & Aims: Liver cancer is a significant global health issue, with its incidence rising in parallel with the obesity epidemic. The limited therapeutic options available emphasize the need for a better understanding of the molecular pathways involved in its pathogenesis. While much of...

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Main Authors: M. Eugenia Delgado, Salvador Naranjo-Suarez, Marta Ramírez-Pedraza, Beatriz I. Cárdenas, Carmen Gallardo-Martínez, Alexandra Balvey, Eulalia Belloc, Judit Martín, Mark Boyle, Raúl Méndez, Mercedes Fernandez
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:JHEP Reports
Subjects:
Translation
Cytoplasmic polyadenylation element binding protein
Ferroptotic cell death
Hepatocellular carcinoma
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555924003008
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