NLRP3 Inflammasome Activation Is Involved in Geniposide-Induced Hepatotoxicity

Conclusions: Our findings collectively elucidate that geniposide induces hepatotoxicity by triggering NLRP3 inflammasome signaling. Inhibition of the inflammasome presents a promising novel therapeutic target for mitigating geniposide-induced hepatotoxicity.

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Bibliographic Details
Main Authors: Yixuan Liu, Baoyue Liu, Mingzhu Shi, Tianxiang Ye, Huifang Li
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/mi/4112856
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