Characterization of intact mRNA-based therapeutics by charge detection mass spectrometry and mass photometry
The impressive success of mRNA-based vaccines to combat COVID-19 has encouraged biopharmaceutical companies to invest in broader applications of alike vaccines for various diseases. Analytical approaches must keep pace to support this surge in the development of mRNA-based therapies. Intact mass ana...
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| Main Authors: | Evolène Deslignière, Lauren F. Barnes, Thomas W. Powers, Olga V. Friese, Albert J.R. Heck |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-06-01
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| Series: | Molecular Therapy: Methods & Clinical Development |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S232905012500049X |
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