Characterization of intact mRNA-based therapeutics by charge detection mass spectrometry and mass photometry

The impressive success of mRNA-based vaccines to combat COVID-19 has encouraged biopharmaceutical companies to invest in broader applications of alike vaccines for various diseases. Analytical approaches must keep pace to support this surge in the development of mRNA-based therapies. Intact mass ana...

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Bibliographic Details
Main Authors: Evolène Deslignière, Lauren F. Barnes, Thomas W. Powers, Olga V. Friese, Albert J.R. Heck
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Molecular Therapy: Methods & Clinical Development
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Online Access:http://www.sciencedirect.com/science/article/pii/S232905012500049X
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