Epigenetic mechanisms of plasticity and resistance in glioblastoma: therapeutic targets and implications

Glioblastoma (GBM), a highly aggressive and malignant form of primary adult brain cancer, poses significant therapeutic challenges. Despite our improved understanding of the cellular and molecular mechanisms underlying tumorigenesis and the evolution of GBM, targeted molecular therapies have failed...

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Bibliographic Details
Main Authors: Farzaneh Amirmahani, Saurav Kumar, Sree Deepthi Muthukrishnan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Epigenetics and Epigenomics
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Online Access:https://www.frontiersin.org/articles/10.3389/freae.2025.1519449/full
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