Knockdown of p53 Enhances LncRNA A2M‐AS1 Inhibition of Pancreatic Cancer Progression via Regulating MAPK Pathway

Knockdown of p53 Enhances LncRNA A2M‐AS1 Inhibition of Pancreatic Cancer Progression via Regulating MAPK Pathway

ABSTRACT Purpose Rapid progression in late‐stage is a characteristic of pancreatic cancer (PC), leading to mortality. The critical role of lncRNA A2M‐AS1 (long non‐coding RNA alpha‐2‐macroglobulin antisense RNA 1) is involved in cancer progression, but the upstream regulator of A2M‐AS1 in the PC pro...

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Main Authors: Yu Cen, Yihui Luo, Yi Nan, Wenxi Kuang, Xianglian Zhang, Jiexia Lu, Chunxiao Xie, Mingzhi Xie, Enran Chen, Haixing Jiang, Shanyu Qin
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Cancer Medicine
Subjects:
LncRNA A2M‐AS1
p53
pancreatic cancer
therapeutic target
Online Access:https://doi.org/10.1002/cam4.70956
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https://doi.org/10.1002/cam4.70956

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