Structure and function of the human apoptotic scramblase Xkr4

Abstract Phosphatidylserine externalization on the surface of dying cells is a key signal for their recognition and clearance by macrophages and is mediated by members of the X-Kell related (Xkr) protein family. Defective Xkr-mediated scrambling impairs clearance, leading to inflammation. It was pro...

Full description

Saved in:
Bibliographic Details
Main Authors: Sayan Chakraborty, Zhang Feng, Sangyun Lee, Omar E. Alvarenga, Aniruddha Panda, Shuming Zhang, Renato Bruni, George Khelashvili, Kallol Gupta, Alessio Accardi
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62739-1
Tags: Add Tag
No Tags, Be the first to tag this record!