Intraoperative nerve-specific fluorescence visualization in head and neck surgery: a Phase 1 trial

Abstract Iatrogenic nerve injury is a surgical complication with significant morbidity. This clinical trial, now complete, investigates the systemic administration of bevonescein, which selectively binds to nerves, in a single-arm, prospective multi-center, dose-escalation Phase 1 trial in adult pat...

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Bibliographic Details
Main Authors: Yu-Jin Lee, Ryan K. Orosco, Michael Bouvet, Jeremy D. Richmon, Brett J. Berman, Kayva L. Crawford, Marisa Hom, Quyen T. Nguyen, Eben L. Rosenthal
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60737-x
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