Synthetic Pre-miRNA-Based shRNA as Potent RNAi Triggers

RNA interference (RNAi) is a powerful tool for studying gene function owing to the ease with which it can selectively silence genes of interest, and it has also attracted attention because of its potential for therapeutic applications. Chemically synthesized small interfering RNAs (siRNAs) and DNA v...

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Bibliographic Details
Main Authors: Kazuya Terasawa, Kazuharu Shimizu, Gozoh Tsujimoto
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Journal of Nucleic Acids
Online Access:http://dx.doi.org/10.4061/2011/131579
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